Prospective observational study of ADLs in elderly patients received lung cancer radiotherapy

Prospective observational study of ADLs in elderly patients received lung cancer radiotherapy - PROBITY

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000059332

Enrollment

100

Registered

2025-10-08

Start date

2025-10-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Age 75 years or older at the time of obtaining informed consent 2) Scheduled to undergo definitive radiotherapy for non-small cell lung cancer 3) No concurrent or sequential chemotherapy planned 4) No prior radiotherapy involving the hilum or mediastinum, including for other cancer types 5) Able to communicate in Japanese and has provided written informed consent to participate in the study

Exclusion criteria

Exclusion criteria: 1) Presence of active double (synchronous) cancer 2) Any other condition judged by the principal investigator to be inappropriate for study participation

Design outcomes

Primary

Measure	Time frame
Proportion of patients without a decline in instrumental activities of daily living (IADL) at 6 months after radiotherapy	—

Secondary

Measure	Time frame
TMIG-IADL(changs), EQ-5D-5L(changes), overall survival, recurrence-free survival, cumulative incidence of recurrence, incidence of adverse events	—

Countries

Japan

Contacts

Public ContactMasaki Nakamura

National Cancer Center Hospital East Radiaiton Oncology

masanaka@east.ncc.go.jp04-7133-1111

Outcome results