Preliminary study on the effect of pre-bedtime oral care on the oral environment upon early morning awakening

Preliminary study on the effect of pre-bedtime oral care on the oral environment upon early morning awakening - Preliminary study on the effect of pre-bedtime oral care on the oral environment upon early morning awakening

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000059273

Enrollment

Registered

2025-10-11

Start date

2025-10-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy people

Interventions

Intervention 1: One day of oral care including brushing and rinsing with mouthwash before going to bed - Two-day washout period - One day of oral care including brushing and rinsing with distilled wat

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Participants who can gargle with mouthwash. 2) Participants who do not normally use mouthwash. 3) Participants who can use the toothpaste used in the study during the study period. 4) Participants who can adjust to the designated wake-up time during the study period.

Exclusion criteria

Exclusion criteria: 1) Subjects currently undergoing dental treatment, such as caries treatment 2) Subjects who have received antibiotic treatment within the past two weeks 3) Subjects with no teeth 4) Subjects who have a habit of drinking fluids between the time of bedtime and the time of waking the next morning

Design outcomes

Primary

Measure	Time frame
Oral bacteria count	—

Countries

Japan

Contacts

Public ContactYukiko Sakamoto

Wakayama Medical University School of Health and Nursing Science

sakamoto-nc@wakayama-med.ac.jp+81-73-446-6700

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026