gingival condition
Conditions
Interventions
Study participants were asked to lick three tablets of a food product containing Lactobacillus salivarius WB21 and epigallocatechin gallate (Avantbise Oral Tablets) daily, one tablet at a time, after
Sponsors
Fukuoka Dental College
Wakamoto Pharmaceutical Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Healthy adult men and women (2) Those who brush their teeth at least twice a day (3) Those with 20 or more teeth
Exclusion criteria
Exclusion criteria: (1) Subjects with any oral symptoms (2) Subjects who regularly smoke (3) Subjects who wear dentures (4) Subjects who have received periodontal treatment within 3 months prior to the start of the study (5) Subjects who have taken antibiotics within 3 months prior to the start of the study (6) Subjects who have used toothpaste, mouthwash, or oral care supplements containing lactic acid bacteria within 1 month prior to the start of the study (7) Subjects with a history of digestive disorders (gastritis, gastric ulcer, colitis, etc.), diabetes, liver disease, kidney disease, serious respiratory disorders such as asthma, serious heart disease, or systemic disorders such as malignant tumors (8) Subjects who are or may be pregnant, or who are breastfeeding (9) Subjects with a history of milk allergies or food allergies to food ingredients (10) Subjects who are otherwise deemed inappropriate participants by the study director (11) Subjects who have participated in other clinical trials within 1 month prior to obtaining consent to participate in this study, or who plan to participate in other clinical trials after obtaining consent to participate in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| gingival health | — |
Secondary
| Measure | Time frame |
|---|---|
| Microbial balance on tongue coating | — |
Countries
Japan
Contacts
Public ContactNao Taniguchi
Fukuoka Dental College Department of Preventive and Public Health Dentistry
Outcome results
None listed