Head and Neck Adenoid Cystic Carcinoma
Conditions
Interventions
The radiation field is defined not only based on the gross tumor volume (GTV) confirmed radiologically on CT and MRI scans taken during treatment planning, but also considering high-risk anatomical st
Relative Biological Effectiveness), and a margin is added to establish the clinical target volume (CTV).CTV is defined in two stages (CTV1: first half, CTV2: second half). For the PNTS (-) group, the
Sponsors
Gunma University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients with histologically confirmed adenoid cystic carcinoma of the head and neck region. 2) Patients with measurable lesions. 3) Patients scheduled to undergo Carbon-ion Radiotherapy. 4) Patients aged 18 years or older. 5) Patients with a Performance Status (PS) of 0-2. 6) Patients who have been informed of their diagnosis and condition and possess the capacity to consent.
Exclusion criteria
Exclusion criteria: 1) Patients with a history of radiation therapy to the target treatment area. 2) Patients with active, refractory infection at the irradiation site. 3) Patients with severe complications (e.g., poorly controlled diabetes, myocardial infarction requiring urgent intervention, unstable angina, poorly controlled arrhythmia, bleeding tendency due to untreated hemorrhagic disease, collagen disease requiring steroid administration). 4) Patients with active multiple cancers (synchronous multiple cancers and metachronous multiple cancers with a disease-free interval of 5 years or less). However, lesions equivalent to carcinoma in situ or mucosal carcinoma, deemed curable by local therapy, are not included in active multiple cancers. 5) Other individuals deemed unsuitable by the attending physician due to medical, psychological, or other factors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 5-year Local Control Rate | — |
Countries
Japan
Contacts
Public ContactAtsushi Musha
Gunma University Heavy Ion Medical Center
Outcome results
None listed