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Effect of oral intake of cocoa-derived polyphenols on muscle fatigue resistance and recovery in humans

Effect of oral intake of cocoa-derived polyphenols on muscle fatigue resistance and recovery in humans - Effect of oral intake of cocoa-derived polyphenols on muscle fatigue resistance and recovery in humans

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000059190
Enrollment
15
Registered
2025-10-03
Start date
2025-10-03
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy participant

Interventions

Test food Cocoa flavanols: 500 mg Theobromine: 180.8 mg Ingestion: 1 time placebo theobromine: 180.8 mg Ingestion: 1 time

Sponsors

Shibaura Institute of Technology
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: - No history of cardiac or cardiovascular disease. - No neuromuscular or orthopedic diseases of the lower body at the time of the experiment, capable of walking independently and performing physical exercise measurements. - Has not smoked for more than six months. - The participant's lifestyle (timing and quantity of meals and sleep) and menstrual cycle should be relatively stable.

Exclusion criteria

Exclusion criteria: - Participants who have not had enough sleep on the night before the measurement day or who have not eaten on the day of the measurement, etc., which may affect the measurement results. - Participants who have a regular exercise habit of at least twice a week

Design outcomes

Primary

MeasureTime frame
- Peak joint torque during maximal voluntary contraction, evoked torque, voluntary activation, muscle activity, salivary chromogranin A before and after muscle fatiguing task - Time to complete the muscle fatigue task

Countries

Japan

Contacts

Public ContactRyota Akagi

Shibaura Institute of Technology Systems engineering and Science

rakagi12@shibaura-it.ac.jp+81-48-720-6020

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026