acute respiratory failure with PaO2/FIO2 less than 300 mmHg and mechanically ventilated
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) The patient exhibits hypoxemia (PaO2/FIO2 below 300 mmHg) and is receiving mechanical ventilation. 2) A central venous line is inserted via the internal jugular vein. 3) The patient is 18 years of age or older at the time of enrollment. 4) Written informed consent for study participation has been obtained from the patient or a legally authorized representative.
Exclusion criteria
Exclusion criteria: 1) Hypotension or heart failure requiring high-dose catecholamine administration. 2) Renal failure requiring dialysis. 3) Hypernatremia (latest sodium value within 1 day prior to registration more than 145 mEq/L). 4) Thoracic deformity observed on chest CT or chest X-ray. 5) Pacemaker implantation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Consistency of distribution of pulmonary blood flow using different methods (measurements with or without ventilation) | — |
Countries
Japan
Contacts
Shimane university hospital Intensive Care Medicine