Correlation Between Non-Perfusion Areas and Retinal Sensitivity in Diabetic Macular Edema Resolved After Anti-VEGF Therapy

Correlation Between Non-Perfusion Areas and Retinal Sensitivity in Diabetic Macular Edema Resolved After Anti-VEGF Therapy - Correlation Between Non-Perfusion Areas and Retinal Sensitivity in Diabetic Macular Edema Resolved After Anti-VEGF Therapy

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000059171

Enrollment

Registered

2025-09-24

Start date

2024-09-19

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetic retinopathy

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with diabetic retinopathy who had previously received anti-VEGF drug treatment for diabetic macular edema at each research institution within the period up to the date of ethics committee approval, and who have not experienced recurrence of edema for six months without anti-VEGF drug treatment, and who underwent visual field measurement using OCTA and Humphrey perimeter. There are no restrictions on other DME treatments, such as anti-VEGF drugs or laser therapy.

Exclusion criteria

Exclusion criteria: 1. Patients who declined to participate in this study 2. Patients with retinal diseases other than DME (e.g., retinal vein occlusion) 3. Patients with neovascular glaucoma

Design outcomes

Primary

Measure	Time frame
Avascular area in OCTA, retinal visual field sensitivity in Humphrey perimeter	—

Secondary

Measure	Time frame
A comparison of vascular density in the avascular area when past macular edema was present and when the edema had subsided was performed.	—

Countries

Japan

Contacts

Public Contactyuki sanada

university of Fukui Hospital Ophthalmology

akasakasakasusa@gmail.com0776-61-8403

Outcome results