glaucoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria:
Exclusion criteria
Exclusion criteria: (1) Individuals who are unable to provide informed consent. (2) Individuals with olfactory dysfunction that prevents adequate perception of odor stimuli (e.g., chronic rhinosinusitis with nasal obstruction, or neurodegenerative diseases associated with hyposmia such as Parkinson's disease or Alzheimer's disease). (3) Individuals with hypersensitivity to essential oils (e.g., who experience unpleasant reactions or allergic responses to aromatic oils). (4) Pregnant or breastfeeding women. (5) Individuals with a history of disorders or current use of medications affecting cortisol secretion (e.g., adrenal, thyroid, or pituitary disorders, or medications known to alter cortisol levels). (6) Individuals with a history of symptomatic hypotension (e.g., orthostatic dizziness, syncope, vasovagal episodes).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Saliva collection (salivary cortisol) Pittsburgh Sleep Quality Index State-Trait Anxiety Inventory Flammer syndrome assessment Heart rate variability Nailfold capillary Ocular blood flow Intraocular pressure Blood pressure Heart rate variability Cerebral activity Visual Analog Scale Essential oil usage and recording | — |
Countries
Japan
Contacts
Tohoku University Graduate School of Medicine Department of Ophthalmology