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Evaluation of the Effects of Aroma on Autonomic Nervous Activity and Ophthalmic Parameters in Patients with Glaucoma

Evaluation of the Effects of Aroma on Autonomic Nervous Activity and Ophthalmic Parameters in Patients with Glaucoma - Evaluation of the Effects of Aroma on Autonomic Nervous Activity and Ophthalmic Parameters in Patients with Glaucoma

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000059154
Enrollment
40
Registered
2025-10-06
Start date
2025-10-14
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glaucoma

Interventions

Sponsors

Tohoku University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria:

Exclusion criteria

Exclusion criteria: (1) Individuals who are unable to provide informed consent. (2) Individuals with olfactory dysfunction that prevents adequate perception of odor stimuli (e.g., chronic rhinosinusitis with nasal obstruction, or neurodegenerative diseases associated with hyposmia such as Parkinson's disease or Alzheimer's disease). (3) Individuals with hypersensitivity to essential oils (e.g., who experience unpleasant reactions or allergic responses to aromatic oils). (4) Pregnant or breastfeeding women. (5) Individuals with a history of disorders or current use of medications affecting cortisol secretion (e.g., adrenal, thyroid, or pituitary disorders, or medications known to alter cortisol levels). (6) Individuals with a history of symptomatic hypotension (e.g., orthostatic dizziness, syncope, vasovagal episodes).

Design outcomes

Primary

MeasureTime frame
Saliva collection (salivary cortisol) Pittsburgh Sleep Quality Index State-Trait Anxiety Inventory Flammer syndrome assessment Heart rate variability Nailfold capillary Ocular blood flow Intraocular pressure Blood pressure Heart rate variability Cerebral activity Visual Analog Scale Essential oil usage and recording

Countries

Japan

Contacts

Public ContactYasuaki Kamata

Tohoku University Graduate School of Medicine Department of Ophthalmology

yasuaki.kamata.e1@tohoku.ac.jp0227177294

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Feb 4, 2026