Efficacy test of the dentifrice

Clinical efficacy study of continuous use of dentifrice NW372 on oral condition - Efficacy test of the dentifrice

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000059129

Enrollment

Registered

2025-09-30

Start date

2025-09-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Use dentifrice NW372 at least twice a day for 6 months Use control dentifrice at least twice a day for 6 months.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Males and females aged 18 to 79 years. 2.Patients receiving regular dental check-ups at Kanagawa Dental University Hospital and staff members of Kanagawa Dental University Hospital. 3.Subjects with gingival recession without inflammation in the maxillary and mandibular central incisors and lateral incisors, exhibiting minimal dental misalignment. 4.Subjects who can use toothpaste in amounts of at least 1 gram and brush their teeth for a minimum of 2 minutes, twice a day. 5.Subjects who agree to use only the specified toothpaste and toothbrush during the trial period (interdental brushes and dental floss are allowed, but the use of other toothpastes, mouthwashes, and liquid toothpastes is not permitted). 6.Subjects with no smoking habits. 7.Subjects who can discontinue high-concentration fluoride applications during the trial period.

Exclusion criteria

Exclusion criteria: 1.Subjects with implants, dentures (false teeth), crowns, fillings near the gingival margin, or root surface caries on the target teeth. 2.Subjects who have undergone periodontal regenerative treatment within the past 6 months. 3.Subjects with smoking habits. 4.Subjects who are already participating in other research at the time of receiving an explanation of the research, or who are scheduled to participate in other research during the period of cooperation for participation in this study. 5.Subjects deemed ineligible based on the diagnosis of a dentist. 6.Subjects who are deemed inappropriate for participation in the study by the principal investigator or research staff due to other reasons, including noncompliance with study obligations.

Design outcomes

Primary

Measure	Time frame
Amount of gingival condition before and after 6 months of dentifrice use	—

Countries

Japan

Contacts

Public ContactShuntaro Sugihara

Kanagawa Dental University Department of Periodontology

sugihara@kdu.ac.jp0468453161

Outcome results