None
Conditions
Sponsors
DRC Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Participants aged 30 to 59 years at the time of obtaining consent. 2) Participants whose Fitzpatrick skin phototype is type II or III. 3) Participants whose dorsal skin allows for the evaluation of minimum erythema dose (MED), and who were judged to have MED in the second to sixth levels of UV radiation at the screening. 4) Participants who are able to visit the test site on all test days.
Exclusion criteria
Exclusion criteria: 1) Participants with photosensitivity disorder. 2) Participants taking medicines affecting the skin sensitivity to light. 3) Participants continuously taking anti-inflammatory medicines at least once a month. 4) Participants undergoing cosmetic treatments affecting the skin, or potent cosmetics. 5) Participants habitually consuming items affecting the skin. 6) Participants with skin conditions or damage, including scars, inflammation or regular skin irritation on their dorsal skin, such as pre/post menstruation. 7) Participants who have been exposed to UV rays beyond daily life during the two months prior to the screening, or cannot refrain from excessive UV exposure during the study period. 8) Participants with serious drug/food allergies or a history of them. 9) Participants currently under treatment or with a history of serious symptoms from malignant tumors or disorders of respiratory, liver, kidney, heart, lung, digestive, blood, endocrine, or metabolic systems. 10) Participants habitually consuming items with lactobacilli, bifidobacteria, oligosaccharides or affecting the intestinal environment. 11) Participants habitually drinking excessive alcohol. 12) Participants with a smoking habit. 13) Participants with a BMI under 17.0 kg/m2 or 28.0 kg/m2 or more. 14) Participants with fewer than three bowel movements per week. 15) Participants with chronic gastrointestinal symptoms such as diarrhea. 16) Participants with irregular lifestyles. 17) Participants planning lifestyle changes, or visit areas with strong UV rays during the study period. 18) Participants who are pregnant, breastfeeding, or planning pregnancy during the study period. 19) Participants who have participated in other studies three months prior to the date of consent, scheduled to participate in studies, or have traces of sunburn on the dorsal skin from previous studies. 20) Participants judged ineligible by principal investigator based on their background.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Minimal erythema dose (MED) | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin color (a*) | — |
Countries
Japan
Contacts
Public ContactYuhma Yoshida
DRC Co., Ltd. Efficacy Testing of Cosmetics and Foods Group
Outcome results
None listed