Type 2 diabetes
Conditions
Interventions
Type 2 diabetes treated with subcutaneous insulin injections for more than 10 years
Patients who have never used subcutaneous insulin injections
Sponsors
Toho university school of medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Patients with type 2 diabetes who was diagnosed for 10 years or more - Patients aged 65 to 90 years - MOCA-J score of 18 to 25 - Patients who have been receiving subcutaneous insulin injections for 10 years or more - Patients who have never received subcutaneous insulin injections - Patients who have provided written consent to participate in the study
Exclusion criteria
Exclusion criteria: - Patients who have been previously diagnosed with dementia - Patients with underlying conditions that cause cognitive impairment - Heavy alcohol users - Patients taking medications that affect cognitive function - Patients for whom PET scans are difficult to perform - Patients deemed inappropriate by their attending physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The standardized uptake volume ratio (SUVr) was calculated using the volumes of interest (VOI) of eight domain (frontal lobe, parietal lobe, temporal lobe, occipital lobe, posterior cingulate gyrus, precuneus, basal ganglia, and cerebellum) and Composite (a composite of eight regions) and the mean pixel values of Pons, and the mean cortical SUVr (mcSUVr) was compared between insulin user group and noninsulin user group. | — |
Countries
Japan
Contacts
Public ContactFukumi Yoshikawa
Toho university school of medicine Division of Diabetes, Metabolism, and Endocrinology, Department of internal medicine.
Outcome results
None listed