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Efficacy of Linked Color Imaging-Assisted Colonoscopy with Artificial Intelligence for Adenoma Detection Rate without Antispasmodic Use: A Multicenter Randomized Controlled Trial

Efficacy of Linked Color Imaging-Assisted Colonoscopy with Artificial Intelligence for Adenoma Detection Rate without Antispasmodic Use: A Multicenter Randomized Controlled Trial - ELIAS trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000059058
Enrollment
210
Registered
2025-09-14
Start date
2025-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon polyp

Interventions

LCI/CADe group: observation from the cecum to the rectum is performed using LCI mode with CADe (CAD EYE: Fujifilm Medical Corporation) assistance. WLI group: observation from cecum to rectum with norm

Sponsors

Nippon Medical School Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. persons aged 20 years and over who undergo a planned colonoscopy. 2. persons undergoing colonoscopy with the purpose of examination as "asymptomatic patients, including second-line screening (screening)", "patients with a history of polypectomy and for follow-up purposes (surveillance)" or 'symptomatic scrutiny' 3. patients who do not wish to use or are clinically unable to use the antispasmodic drug butylscopolamine bromide (cardiac disease, history of angle closure glaucoma or glaucoma, benign prostatic hyperplasia, history of hyperthyroidism, drug allergy, etc.) 4. those who do not wish to use or are clinically unable to use the antispasmodic drug glucagon (e.g. history of diabetes, blood glucose and HbA1c not measured by blood sampling within 1 month of the examination and diabetes cannot be ruled out) 5. persons for whom the study has been explained in writing and written consent has been obtained.

Exclusion criteria

Exclusion criteria: 1. those with a history of inflammatory bowel disease 2. persons with active gastrointestinal bleeding 3. who have undergone bowel resection 4. those with a history of familial adenomatous polyposis 5. persons with previously known severe intestinal adhesions 6. any other person who is judged by the principal investigator or principal study investigator to be unsuitable to participate in the study.

Design outcomes

Primary

MeasureTime frame
adenoma detection rate

Countries

Japan

Contacts

Public ContactTsugumi Habu

Nippon Medical School Hospital Department of Gastroenterology

t-habu@nms.ac.jp0338222131

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026