None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy individuals between the ages of 20 and 60. 2. Individuals who drink alcohol regularly (at least three times a week, 10g per session (equivalent to 350ml of beer)). 3. Individuals with mild skin symptoms (a score of 2 or higher on the DLQI questionnaire). 4. Individuals who fully understand the purpose of this study and agree to participate in it.
Exclusion criteria
Exclusion criteria: 1. Individuals who the principal investigator or co-investigator deems inappropriate for this study. 2. Individuals diagnosed with lifestyle-related disease #2 at the time of participation and receiving oral medication. 3. Individuals receiving oral medication for cerebrovascular, cardiovascular, pulmonary, digestive, renal, or autoimmune diseases at the time of participation. 4. Individuals who have used hydrogen products within the past week at the time of consent. 5. Individuals who plan to use hydrogen products after consenting until the end of the study. 6. Individuals with dementia or psychiatric disorders who are unable to understand the significance of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in heart rate variability data before and after intervention (after 9 weeks) | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in heart rate variability data before and after intervention (after 5 weeks), Patient Health Questionnaire-9 (PHQ-9), Pittsburgh Sleep Quality Index, new version of the STAI State-Trait Anxiety Inventory, DLQI questionnaire, SKINDEX29 questionnaire, VOCs at rest, stratum corneum moisture content, and transepidermal water loss before and after intervention (after 5 and 9 weeks) | — |
Countries
Japan
Contacts
Keio University School of Medicine, Institute for Integrated Sports Medicine