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J-RESPECT2 study: Japan CompREhenSive Process for End-of-Life Care and Organ DonaTion after Brain Death

J-RESPECT2 study: Japan CompREhenSive Process for End-of-Life Care and Organ DonaTion after Brain Death - J-RESPECT2 study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000059018
Enrollment
1000
Registered
2025-09-15
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute brain injuries such as post-cardiac arrest syndrome, severe traumatic brain injury, and severe stroke

Interventions

None listed

Sponsors

Okayama University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients admitted to the ICU between the date of approval by the head of the research institution and December 31, 2027, after emergency department presentation or emergency transport, with severe brain injury, receiving mechanical ventilation, and presenting, except immediately prior to death confirmation, with deep coma (Glasgow Coma Scale score of 3) and bilateral fixed dilated pupils (4 mm or greater), in a state judged not to be influenced by sedatives or other medications. 2. Male and female patients of all ages. 3. Including those transferred from other hospitals.

Exclusion criteria

Exclusion criteria: 1. Patients transferred from a referring hospital more than 24 hours after the initial visit or transport to that hospital. 2. Patients transferred from a general ward, admitted to the ICU for the first time during that hospitalization. 3. Patients in which no key family member is available. 4. Patients deemed inappropriate by the attending physician.

Design outcomes

Primary

MeasureTime frame
Organ donation after brain death

Countries

Japan

Contacts

Public ContactTetsuya Yumoto

Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University Department of Emergency, Critical Care and Disaster Medicine

tyumoto@cc.okayama-u.ac.jp086-235-7426

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026