Clinical management algorithm for embolic stroke of undetermined source

Clinical management algorithm for embolic stroke of undetermined source - ALGO-ESUS

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000059015

Enrollment

500

Registered

2025-09-06

Start date

2025-09-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Embolic stroke of undetermined source (ESUS)

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who experienced an ischemic stroke between January 2021 and April 2025 and visited or were admitted to the participating institution. 2. Patients diagnosed with embolic stroke of undetermined source.

Exclusion criteria

Exclusion criteria: Patients who did not consent to participate.

Design outcomes

Primary

Measure	Time frame
1. Incidence of recurrent stroke during follow-up 2. Characteristics of patients with implantable loop recorders or electrocardiogram patch monitors 3. Timing of atrial fibrillation detection and atrial fibrillation burden	—

Secondary

Measure	Time frame
1. Timing of atrial fibrillation detection and AF burden after PFO closure 2. Antithrombotic therapy and ischemic or bleeding events after percutaneous PFO closure	—

Countries

Japan

Contacts

Public ContactJunji Takasugi

The University of Osaka Graduate School of Medicine Department of Neurology

takasugi@neurol.med.osaka-u.ac.jp06-6879-3571

Outcome results