Perioperative Neurocognitive Disorders (PND)
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients who meet all of the following criteria will be included: 1. Patients undergoing surgery under general anesthesia at Hamamatsu University Hospital who are admitted to the ICU. 2. Patients judged by the attending physician to be eligible for participation in this study. 3. Patients who have provided written informed consent for participation in this study.
Exclusion criteria
Exclusion criteria: Patients who meet any of the following criteria will be excluded from the study: 1. Patients from whom collection of residual blood samples is difficult, requiring additional blood sampling, and who either did not provide consent or withdrew consent. 2. Patients judged by the attending physician to be inappropriate for participation. 3. Patients who already present with cognitive impairment at the time of hospital admission or in the preoperative phase.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PND onset and the dynamics of biological and digital biomarkers, together with RNA signaling pathways, associated with sleep and psychiatric disorders | — |
Countries
Japan
Contacts
Hamamatsu University School of Medicine Department of Hospital Pharmacy