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Prognostic impact of MES 1 inflammatory extent on remission maintenance in ulcerative colitis

Prognostic impact of MES 1 inflammatory extent on remission maintenance in ulcerative colitis - Prognostic impact of MES 1 inflammatory extent on remission maintenance in ulcerative colitis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000058934
Enrollment
300
Registered
2025-08-29
Start date
2025-08-29
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ulcerative colitis

Interventions

None listed

Sponsors

Dokkyo Medical University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with UC who were treated at the Department of Gastroenterology, Dokkyo Medical University Hospital between January 1, 2008, and December 31, 2023, had an MES of 0 or 1 at the initial endoscopic assessment after remission induction therapy without any change in remission maintenance therapy, and had available follow-up data for two years after the endoscopy were enrolled.

Exclusion criteria

Exclusion criteria: The following cases were excluded from the study: cases with left-sided colitis or proctitis; cases in which no endoscopic examination was performed after remission induction; cases in which total colonoscopy was not performed; cases that had an MES of 2 or 3 at the initial endoscopic assessment after remission induction therapy; cases in which the clinical course could not be followed for two years after endoscopy; cases with a history of colonic surgery; cases receiving immunosuppressive therapy for other diseases; cases in which the patient refused to participate in the study; and cases deemed inappropriate for inclusion in this study by the investigators.

Design outcomes

Primary

MeasureTime frame
The primary endpoint of this study is to evaluate the two-year clinical remission maintenance rate based on the extent of inflammation classified as MES 1.

Countries

Japan

Contacts

Public ContactMimari Kanazawa

Dokkyo Medical University School of Medicine Department of Gastroenterology

mimari77@dokkyomed.ac.jp+81-282-87-2147

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026