Healthy adults will be enrolled.
Conditions
Interventions
Participants will stay in a hypoxic chamber for 1 hour per day, 5 days per week, for 3 weeks.
Participants will stay in a hypoxic chamber for 1 hour per day, 5 days per week, for 3 weeks.
Sponsors
Tohoku University
Regenesom Inc.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Healthy individuals without a history of cardiovascular, internal medicine, or respiratory diseases 2. Aged 20 years or older and 65 years or younger at the time of enrollment 3. Not on any regular medication 4. Able to provide written informed consent for study participation
Exclusion criteria
Exclusion criteria: Participants meeting the following conditions will be excluded due to anticipated vulnerability or hypersensitivity to hypoxic exposure: 1. History of cardiovascular or respiratory disease, or currently under treatment for such conditions 2. Current smoking habit 3. History of an acute internal medicine illness (e.g., cold, bronchitis, or other infection) requiring medical consultation within the past two weeks Participants meeting the following conditions will be excluded as they may affect the evaluation of effectiveness: 1. Currently under treatment for diabetes mellitus or hypertension 2. Regular use of medication 3. Claustrophobia 4. Metal allergy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Circadian blood glucose variability will be assessed during a three-week intervention consisting of hypoxic exposure for 1 hour per day, 5 days per week. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in blood oxygen saturation and blood pressure will be examined during a three-week intervention consisting of hypoxic exposure for 1 hour per day, 5 days per week. | — |
Countries
Japan
Contacts
Public ContactTaku Nakai
Tohoku University Graduate School of Medicine Division of Oxygen Biology
Outcome results
None listed