Identification of effective interventions for preventing the need for long-term care in older multi-morbid inpatients and outpatients

Identifying intervention patterns that contribute to improving frailty in older multi-morbid patients using a patient registry containing multifaceted and longitudinal data. - Identification of intervention patterns contributing to the improvement of frailty in older multi-morbid patients

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000058903

Enrollment

600

Registered

2025-09-01

Start date

2025-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute diseases (fractures, pneumonia, heart failure, etc.), lifestyle-related diseases

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who meet at least one of the J-CHS criteria 2. Patients aged 65 years or older 3. Outpatients or inpatients 4. Patients who have provided written consent

Exclusion criteria

Exclusion criteria: Patients deemed unsuitable for this trial by the principal investigator or sub-investigator

Design outcomes

Primary

Measure	Time frame
Changes in FIM (Functional Independence Measure)	—

Secondary

Measure	Time frame
<Inpatients: From admission to discharge, Outpatients: From arrival to 12, 24 weeks after arrival> Changes in CFS (Clinical Frailty Scale) Comprehensive Geriatric Assessment (CGA) 1. Basic Activities of Daily Living: Barthel Index 2. Instrumental Activities of Daily Living: Lawton & Brody Scale 3. Motivation: Vitality Index 4. Cognitive Function: MMSE-J 5. Mood/Emotional State: GDS-15 (GDS-5) 6. Apathy: Motivation Score Muscle Strength (Grip Strength), Physical Function (SPPB, TUG), Body Composition (Skeletal Muscle Mass, Body Fat Mass, Bone Mass, Phase Angle) GLIM criteria Mini Nutritional Assessment-Short Form: MNA-SF, MUST Severity of geriatric syndromes (delirium, dysphagia, pain, falls, nocturia, insomnia, etc.) Medications used (number, dosage, timing of administration) Japanese version of the Anticholinergic Scale Quality of Life (QOL) scale: EQ-5D Patient Experience (PX): Inpatients (HCAHPS), Outpatients (CG-CAHPS) Zarit Caregiver Burden Scale (inpatients) Comorbidities (CCI) Management status of lifestyle-related diseases Dietary content and intake (inpatients) Rehabilitation units (inpatients) Dental-related items: Number of remaining teeth, occlusal support area, severity of periodontitis, presence of dentures or tooth pain (inpatients) <Inpatients: Follow-up period (12 weeks post-discharge)> QOL (EQ-5D), Zarit Caregiver Burden Scale, readmission status, change in care setting, mortality <Temporal intervention effect assessment (selected cases)> Inpatients: Wearable device (SOKAI RING)	—

Measure

Time frame

<Inpatients: From admission to discharge, Outpatients: From arrival to 12, 24 weeks after arrival> Changes in CFS (Clinical Frailty Scale) Comprehensive Geriatric Assessment (CGA) 1. Basic Activities of Daily Living: Barthel Index 2. Instrumental Activities of Daily Living: Lawton & Brody Scale 3. Motivation: Vitality Index 4. Cognitive Function: MMSE-J 5. Mood/Emotional State: GDS-15 (GDS-5) 6. Apathy: Motivation Score Muscle Strength (Grip Strength), Physical Function (SPPB, TUG), Body Composition (Skeletal Muscle Mass, Body Fat Mass, Bone Mass, Phase Angle) GLIM criteria Mini Nutritional Assessment-Short Form: MNA-SF, MUST Severity of geriatric syndromes (delirium, dysphagia, pain, falls, nocturia, insomnia, etc.) Medications used (number, dosage, timing of administration) Japanese version of the Anticholinergic Scale Quality of Life (QOL) scale: EQ-5D Patient Experience (PX): Inpatients (HCAHPS), Outpatients (CG-CAHPS) Zarit Caregiver Burden Scale (inpatients) Comorbidities (CCI) Management status of lifestyle-related diseases Dietary content and intake (inpatients) Rehabilitation units (inpatients) Dental-related items: Number of remaining teeth, occlusal support area, severity of periodontitis, presence of dentures or tooth pain (inpatients) <Inpatients: Follow-up period (12 weeks post-discharge)> QOL (EQ-5D), Zarit Caregiver Burden Scale, readmission status, change in care setting, mortality <Temporal intervention effect assessment (selected cases)> Inpatients: Wearable device (SOKAI RING)

—

Countries

Japan

Contacts

Public ContactKEN SUGIMOTO

Kawasaki Medical School General Geriatric Medicine

ksugimoto@med.kawasaki-m.ac.jp086-225-2112

Outcome results