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Diagnostic Performance of FFR-CT for Detecting Functional Ischemia in Patients with Moderate Stenosis on Coronary CT Performed for the Evaluation of Stable Angina: A Systematic Review and Meta-Analysis

Diagnostic Performance of FFR-CT for Detecting Functional Ischemia in Patients with Moderate Stenosis on Coronary CT Performed for the Evaluation of Stable Angina: A Systematic Review and Meta-Analysis - Diagnostic Performance of FFR-CT for Detecting Functional Ischemia in Patients with Moderate Stenosis on Coronary CT Performed for the Evaluation of Stable Angina: A Systematic Review and Meta-Analysis

Status
Recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000058884
Enrollment
Unknown
Registered
2025-08-26
Start date
2024-09-17
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease

Interventions

None listed

Sponsors

Yokohama City University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Studies were eligible if they evaluated the diagnostic performance of CT-FFR using invasive FFR < 0.80 as the reference standard in patients undergoing coronary CT for the evaluation of stable angina, including those with moderate stenosis. Eligible outcomes included the diagnostic accuracy of CT-FFR in all patients, in patients with moderate stenosis, and stratified by different software. Only original research articles with clearly defined study populations and sufficient quantitative data (e.g., sensitivity, specificity, or AUC) compared against invasive FFR were included.

Exclusion criteria

Exclusion criteria: Reviews, case reports, conference abstracts, and non-human studies were excluded. Studies that did not use FFR < 0.80 as the reference standard, did not provide sufficient quantitative data on CT-FFR diagnostic performance, or were duplicate publications were also excluded. Articles not published in English were excluded as well.

Design outcomes

Primary

MeasureTime frame
(Outcomes Based on FFR < 0.80 as the Reference Standard) Outcome 1: Diagnostic accuracy of CT-FFR in all patients Outcome 2: Diagnostic accuracy of CT-FFR in patients with moderate stenosis Outcome 3: Diagnostic accuracy of CT-FFR according to different software in patients with moderate stenosis

Countries

Japan

Contacts

Public ContactShingo Kato

Yokohama City University Hospital Department of Diagnostic Radiology

shingo.m12226@gmail.com0457872800

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026