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Effect of NP-FES (Electrical Stimulation) on Hand Blood Flow in Elderly Stroke Patients Differences Between Severe and Mild Paralysis

Differential Peripheral Circulatory Responses to Neuroprosthetic Functional Electrical Stimulation (NP-FES) in Elderly Stroke Patients With Severe and Mild Hemiplegia - NP-FES Circulation Trial (NP-FES-CirT)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000058828
Enrollment
20
Registered
2025-08-21
Start date
2023-01-05
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic post-stroke hemiplegia

Interventions

Electrical stimulation (70 Hz, 120 ms) is applied to the paretic extensor muscles, triggered by electromyographic signals from the non-paretic side, to induce joint movement. Stimulation is deliver

Sponsors

Gunma Paz University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with chronic stroke, at least 1 year after onset Hemiplegia with Brunnstrom Recovery Stage of 2 or below, or 5 or above Age 20 years or older Written informed consent obtained from the participant

Exclusion criteria

Exclusion criteria: Patients with cognitive impairment that makes it difficult to understand the study or provide informed consent Patients with severe cardiac, respiratory, or orthopedic conditions that preclude safe intervention Patients with skin disease, infection, or injury at the electrode placement site Patients with implanted electronic devices such as pacemakers

Design outcomes

Primary

MeasureTime frame
Estimated blood flow (Q), calculated using a model combining volume waveform, skin temperature, and hemoglobin concentration. Measurement timing: before stimulation, immediately after stimulation, and 3 minutes post-stimulation Evaluation points: baseline (0 week), week 2, and week 4

Secondary

MeasureTime frame
Patient-reported outcomes obtained through questionnaire/semi-structured interview: subjective experience (usability, cold sensation, pain), changes in self-efficacy, and initiation of daily use

Countries

Japan

Contacts

Public ContactMasaya Tanabe

Faculty of Rehabilitation, Gunma Paz University Department of Physical Therapy

tanabe@paz.ac.jp027-365-3366

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026