Screening for cardiac amyloidosis in patients with carpal tuunel syndrome (SCREEN-CTS trial)

Prospective observational study for screening cardiac amyloidosis in patients with synovial amyloid deposition identified during carpal tunnel release surgery - SCREEN-CTS Trial

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000058808

Enrollment

200

Registered

2025-08-15

Start date

2025-08-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

carpal tunnel syndrome

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients who underwent carpal tunnel release surgery at the Department of Orthopedic Surgery, Tokuyama Central Hospital. (2) Patients who consented to a synovial tissue pathology examination.

Exclusion criteria

Exclusion criteria: (1) Patients diagnosed with cardiac amyloidosis before undergoing carpal tunnel release. (2) Patients diagnosed with AL amyloidosis (primary amyloidosis), dialysis-associated amyloidosis, pregnant patients, and patients with fractures or injuries. (3) Patients with dementia for whom it is difficult to obtain consent.

Design outcomes

Primary

Measure	Time frame
Prevalence and incidence of cardiac amyloidosis	—

Secondary

Measure	Time frame
Time to diagnosis and treatment adoption rate	—

Countries

Japan

Contacts

Public ContactTakatoshi Wakeyama

Japan Community Healthcare Organization Tokuyama Central Hospital Division of Cardiology

wakeyama@icloud.com+81-834-28-4411

Outcome results