Healthy volunteers
Conditions
Interventions
Continuous intake of tablets containing test substance for 4 weeks
No intake of tablets containing test substance
Sponsors
Kyushu University
MACROMILL, INC. Synapse planning Co.,Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Healthy infants (4-6 years old) 2)Guardians receiving a sufficient briefing of the objective and content of the present study, fully understanding and agreeing to voluntarily participate in the study and being able to personally sign a written informed consent
Exclusion criteria
Exclusion criteria: 1) Subjects who consciously use products claiming to be effective, such as test substance. 2) Subjects who have been diagnosed with caries by screening tests 3) Subjects undergoing dental caries treatment 4) Subjects who have declared that they have an allergy to the research food 5) Guardians who are participating in the test of ingesting other foods or medicines, and those who are willing to participate 6) Subjects taking antibiotics or antibacterial agents, or who have taken them within 3 months of the screening test 7) Subjects with a history of congenital or circulatory diseases 8) Others who are judged by the investigator to be inappropriate as subjects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral microbiota | — |
Secondary
| Measure | Time frame |
|---|---|
| Dental caries experience, oral dental status (dental plaque, tongue coating), snacking habits | — |
Countries
Japan
Contacts
Public ContactMikari Asakawa
Kyushu University Section of Preventive and Public Health Dentistry, Faculty of Dental Science
Outcome results
None listed