healthy adult males
Conditions
Interventions
rest hypercapnia (5%CO2 + 21%O2 + N2 balance)->
(washout)->
handgrip exercise (30% of maximal voluntary contraction)->
warming the periocular area (45 degrees Celsius)
rest->
warming the periocular area (45 degrees Celsius)->
hypercapnia(5%CO2 + 21%O2 + N2 balance)->
handgrip exercise (30% of maximal voluntary contraction))
rest->
low-intensity handgrip exercise (10% of maximal voluntary contraction)->
mild-intensity handgrip exercise (30% of maximal voluntary contraction)->
high-intensity handgrip exercise (50% of maximal voluntary contraction)
rest->
Sponsors
Kitasato University
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Healthy adults without chronic disease Participants who provided informed consent after receiving an explanation of the study protocol Participants whose lifestyle habits, such as physical activity and dietary intake, do not undergo significant changes on the day before or the day of the experiment
Exclusion criteria
Exclusion criteria: Participants who have been advised by a physician to refrain from exercise Participants who have been diagnosed with electrocardiographic abnormalities or heart disease by a physician Participants who have experienced sudden loss of consciousness or episodes of palpitations Participants who currently have or have had Kawasaki disease or rheumatic fever Participants who currently have or have had eye diseases Participants who have been diagnosed with anemia or received treatment for anemia by a physician Participants whose compliance with the study protocol is in doubt
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ocular blood flow, pulse waveform variables | — |
Secondary
| Measure | Time frame |
|---|---|
| Grip strength, respiratory parameters, blood flow velocity in middle cerebral artery, blood pressure, heart rate, intraocular pressure, ocular surface temperature | — |
Countries
Japan
Contacts
Public ContactTsukasa IKEMURA
Kitasato University College of Liberal Arts and Sciences
Outcome results
None listed