A Study to Examine the Effects and Safety of Massage

Evaluation of the Effects of Taktipro on Oxytocin Secretion, Stress Reduction, and Safety: An Extended Crossover Trial - TOPS Trial (Taktipro's effect on Oxytocin secretion, Psychological stress, and Safety)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000058706

Enrollment

Registered

2025-09-30

Start date

2025-09-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Normal adults

Interventions

Tactile massage Receptive music therapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy Volunteer

Exclusion criteria

Exclusion criteria: Individuals with heart disease Individuals taking medications that affect the autonomic nervous system Individuals with a history of epilepsy or psychiatric disorders Individuals who are pregnant

Design outcomes

Primary

Measure	Time frame
Salivary concentrations of oxytocin	—

Secondary

Measure	Time frame
Salivary cortisol concentration Assessment of autonomic nervous function by heart rate variability (HRV) analysis Japanese version of the State-Trait Anxiety Inventory (STAI) Vital signs	—

Countries

Japan

Contacts

Public ContactYukie IWASA

Tokushima University Graduate School of Biomedical Sciences

iwasa.yukie@tokushima-u.ac.jp0886339005

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026