coronary microvascular dysfunction
Conditions
Interventions
None listed
Sponsors
Kobe University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (i) Patients with ischaemic symptoms such as chest pain and no obvious significant stenosis (>50%) on coronary angiography (ii) Patients who have undergone invasive coronary function assessment (CFR and IMR) using a pressure wire (iii) Patients who have undergone coronary computed tomography angiography within 120 days before or after coronary angiography (iv) Patients aged 20 years or over who are eligible for consent
Exclusion criteria
Exclusion criteria: (i) Patients with >=50% stenosis or occlusive lesion in any of the three branches or side branches with a vessel diameter of >=1.5 mm or fractional flow reserve (FFR) <=0.8 at coronary angiography (ii) Patients with a history of acute coronary syndrome (iii) Patients who have undergone revascularisation (percutaneous coronary intervention, coronary artery bypass grafting) in the past (iv) Patients with suspected hypertrophic cardiomyopathy, cardiac amyloidosis, or Fabry's disease (v) Patients with moderate or severe valvular disease (vi) Patients undergoing coronary perfusion assessment after cardiac surgery or percutaneous coronary intervention (vii) Patients with inadequate quality of coronary computed tomography angiography images and inability to assess PCAT attenuation (viii) Patients who refused to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnosis of coronary microcirculatory impairment by attenuation of CT values of pericoronary adipose tissue measured by coronary CT within 120 days before and after a coronary angiography procedure. | — |
Countries
Japan
Contacts
Public ContactTakayoshi Toba
Kobe University Hospital Department of Internal Medicine
Outcome results
None listed