Impact of Resting Full-cycle Ratio on Clinical Outcomes in Patients on Hemodialysis

Impact of Resting Full-cycle Ratio on Clinical Outcomes in Patients on Hemodialysis - RFR-HD study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000058674

Enrollment

260

Registered

2025-08-04

Start date

2025-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease on hemodialysis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with age 20 years or older at the time of enrollment Patients on hemodialysis Patients with or suspected coronary artery disease Patients with RFR measurement

Exclusion criteria

Exclusion criteria: Patients with acute myocardial infarction Patients with hemodynamic instability Patients with decompensated heart failure Patients treated by coronary revascularization for target vessel based on RFR Patients with RFR measurement for coronary artery bypass graft Patients with a life expectancy of 12 months or less Others who are judged to be inappropriate as research subjects by the principal investigator

Design outcomes

Primary

Measure	Time frame
Composite of cardiac death, target vessel myocardial infarction, and clinical driven target vessel revascularization	—

Secondary

Measure	Time frame
Individual outcomes of the primary end point. all-cause death, non-target vessel myocardial infarction, and clinical driven non-target vessel revascularization.	—

Countries

Japan

Contacts

Public ContactSeiji Koga

Juntendo University Nerima Hospital Department of Cardiology

kogase@juntendo.ac.jp03-5923-3111

Outcome results