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The clinical differences based on the subtype of primary aldosteronism: Phase 2

The clinical differences based on the subtype of primary aldosteronism: Phase 2 - The clinical differences based on the subtype of primary aldosteronism: Phase 2

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000058658
Enrollment
1000
Registered
2025-07-31
Start date
2025-07-09
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary aldosteronism

Interventions

None listed

Sponsors

Division of Nephrology, Hypertension and Endocrinology, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan
Lead Sponsor
Institute of Science Tokyo hospital, Affiliated Hospital of Chongqing Medical University, Monash University, and Hudson Institute of Medical Research
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who were diagnosed with primary aldosteronism and essential hypertension at Nihon University Itabashi Hospital (January 1, 2006 - January 1, 2030). 2. Patients who were diagnosed with primary aldosteronism and essential hypertension at Institute of Science Tokyo Hospital, Affiliated Hospital of Chongqing Medical University, Monash University, and Hudson Institute of Medical Research (January 1, 2006 - January 1, 2030).

Exclusion criteria

Exclusion criteria: Patients who refused to participate in this study and the investigator determined to be unsuitable for study

Design outcomes

Primary

MeasureTime frame
age, gender, blood pressure, BMI, blood tests (serum biochemistry test, daily fluctuation of hormones, etc.), urinalysis, confirmatory tests(captopril challenge test, furosemide and upright posture test, saline infusion test), contrast CT examination, adrenal vein sampling, portable polysomnography, ankle brachial pressure index, cardiac ultrasound, abdominal ultrasound, carotid ultrasound

Secondary

MeasureTime frame
Proteins presumed to be involved in primary aldosteronism, comprehensive protein profiling using omics platforms, and non-coding RNA

Countries

Japan,Asia(except Japan),Australia

Contacts

Public ContactHiroki Kobayashi

Nihon University School of Medicine Division of Nephrology, Hypertension and Endocrinology, Department of Internal Medicine

kobayashi.hiroki@nihon-u.ac.jp+81-3-3972-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026