An Exploratory Study on the Effects of Short-Term Oligonol Supplementation on High-Altitude Training Adaptation in Female Long-Distance Runners

An Exploratory, Double-Blind, Placebo-Controlled, Parallel-Group Study on the Effects of Oligonol Supplementation on High-Altitude Adaptation in Female Track and Field Athletes (OLIFAT study) - OLIFAT study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000058589

Enrollment

Registered

2025-07-28

Start date

2025-08-16

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female Athletes

Interventions

Participants will orally take one hard capsule containing 100 mg of Oligonol after breakfast and one after dinner (2 capsules per day), with water or lukewarm water. The supplementation period will be

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: (1) Written informed consent has been obtained from the participant. (2) The participant is a healthy female aged 18 years or older. (3) The participant does not plan to take any new supplements or health foods during the study period.

Exclusion criteria

Exclusion criteria: (1) Individuals with a current or past history of allergy to any component contained in the study food. (2) Current smokers or individuals with a history of smoking within the past three months. (3) Individuals who are pregnant, lactating, possibly pregnant, or planning to become pregnant or breastfeed during the study period. (4) Individuals with gastrointestinal disorders that may impair nutrient absorption, such as malabsorption syndrome or a history of gastrectomy. (5) Individuals receiving ongoing pharmacological treatment for any medical condition, including endocrine disorders. (6) Individuals currently participating in another clinical or observational study, or planning to participate in one during the study period. (7) Individuals deemed inappropriate for study participation by the principal investigator.

Design outcomes

Primary

Measure	Time frame
Ferritin concentrations in blood before and after 9-day Oligonol supplementation	—

Secondary

Measure	Time frame
All measurements were conducted before and after 9-day Oligonol supplementation, including: 1. Anemia-related parameters (Reticulocyte count, Total protein, Hemoglobin, Hematocrit, Red blood cell count, Mean corpuscular volume, Mean corpuscular hemoglobin concentration, Total iron-binding capacity, Serum iron) 2. C-reactive protein (CRP) 3. Oxidative stress marker: d-ROMs test 4. Antioxidant capacity: BAP test	—

Measure

Time frame

All measurements were conducted before and after 9-day Oligonol supplementation, including: 1. Anemia-related parameters (Reticulocyte count, Total protein, Hemoglobin, Hematocrit, Red blood cell count, Mean corpuscular volume, Mean corpuscular hemoglobin concentration, Total iron-binding capacity, Serum iron) 2. C-reactive protein (CRP) 3. Oxidative stress marker: d-ROMs test 4. Antioxidant capacity: BAP test

—

Countries

Japan

Contacts

Public ContactNaho Serizawa

Toyo University Faculty of Health and Sports Sciences

serizawa@toyo.jp03-5924-2819

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026