Sex difference in sensory gating with consideration of the menstrual cycle

Sex difference in sensory gating with consideration of the menstrual cycle - Sex difference in sensory gating with consideration of the menstrual cycle

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000058420

Enrollment

Registered

2025-07-31

Start date

2025-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy adults

Interventions

Electrical Stimulation Auditory Stimulation EEG Electrical Stimulation Auditory Stimulation EEG Electrical Stimulation Auditory Stimulation EEG

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Right-handed normal adult men and women Females are normal menstruating adults (menstrual cycle of 28 to 35 days) Adults with no history of psychiatric or neurological disorders

Exclusion criteria

Exclusion criteria: Adults with no history of psychiatric or neurological disorders Women with irregular menstruation

Design outcomes

Primary

Measure	Time frame
To investigate the effects of sex differences taking the menstrual cycle into account on sensory gating in the human brain, we recorded somatosensory evoked potentials (SEPs) and auditory evoked potentials (AEPs) using electroencephalography (EEG) and evaluated the influence of both the menstrual cycle and sex differences. Female participants were assessed during two distinct phases; the menstrual phase (2-4 days after the onset of menstruation) and the ovulatory phase (2-3 days after a positive result using an ovulation prediction kit). Ovulation was evaluated via a urine based test. This approach allows us to examine differences in sensory gating attributable to the menstrual cycle and sex. As a result, we aim to clarify whether sensory information processing in the brain differs according to menstrual phase or biological sex.	—

Measure

Time frame

To investigate the effects of sex differences taking the menstrual cycle into account on sensory gating in the human brain, we recorded somatosensory evoked potentials (SEPs) and auditory evoked potentials (AEPs) using electroencephalography (EEG) and evaluated the influence of both the menstrual cycle and sex differences. Female participants were assessed during two distinct phases; the menstrual phase (2-4 days after the onset of menstruation) and the ovulatory phase (2-3 days after a positive result using an ovulation prediction kit). Ovulation was evaluated via a urine based test. This approach allows us to examine differences in sensory gating attributable to the menstrual cycle and sex. As a result, we aim to clarify whether sensory information processing in the brain differs according to menstrual phase or biological sex.

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Countries

Japan

Contacts

Public ContactSayaka Anazawa

Niigata University of Health and Welfare Graduate School of Health and Welfare Studies

hwd24012@nuhw.ac.jp070-2029-1720

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026