Colorectal cancer
Conditions
Interventions
None listed
Sponsors
Kyoto University
1.Medical Oncology, Kochi Medical School Hospital 2.Clinical Oncology, Kansai Medical University Hospital 3.Division of Translational Research, Center for Medical Research and Development, Division of Translational Research, Osaka Medical and Pharmaceutical University Osaka Medical and Pharmaceutical University 4.Department of Surgery, Kurume University 5.Department of Clinical Laboratory Medicine, Kurume University Hospital 6.Department of Gastroenterological Surgery, Nippon Medical School
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients with colorectal cancer scheduled to undergo chemotherapy at Kyoto University Hospital, Kochi University Hospital, Kansai Medical University Hospital, Osaka Medical and Pharmaceutical University Hospital, Kurume University Hospital, and Nippon Medical School Hospital 2.Informed consent forms for clinical research related to the establishment of cancer spheroids using colorectal cancer tissues were obtained from research collaborators at Kyoto University Hospital, Kochi University Hospital, Kansai Medical University Hospital, Osaka Medical and Pharmaceutical University Hospital, Kurume University Hospital, and Nippon Medical School Hospital. The cases in which spheroid culture models were established or are planned to be established in this study
Exclusion criteria
Exclusion criteria: 1. Cases where treatment efficacy cannot be assessed using RECIST 2. Other cases deemed ineligible for this study by the principal investigator and researcher
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The correlation between drug sensitivity assay results using patient-derived samples (IC50 and AUC) and clinical chemotherapy outcomes in patients, including RECIST-based treatment response, duration of response, and prognosis | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of the estimation results from novel cell imaging technology to those from conventional luciferase assay | — |
Countries
Japan
Contacts
Public ContactObama Kazutaka
Graduate School of Medicine, Kyoto University Department of Surgery, Department of Personalized Cancer Medicine
Outcome results
None listed