Healthy children
Conditions
Interventions
Daily ingestion of powdered lactic acid bacteria for 24 weeks.
Daily ingestion of placebo powder for 24 weeks.
Sponsors
Hokkaido Information University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Subjects who are between the ages of 2 and 5 years old. 2. Subjects whose parents agree to participate in this study with a written informed consent.
Exclusion criteria
Exclusion criteria: 1. Subjects with serious hepatic, renal, cardiac, lung, gastrointestinal, blood, brain, endocrine or metabolic diseases, and/or with serious medical history of those disease. 2. Subjects who regularly use oral or nasal medications. 3. Subjects who regularly use steroids. 4. Subjects who regularly take foods that affect immune function. 5. Subjects with severe perennial and/or seasonal allergic symptoms. 6. Subjects at risk of allergic reactions to drugs or foods. 7. Subjects who participated in clinical studies of other drugs and foods within the last 4 weeks prior to the current study. 8. Subjects who are deemed ineligible by the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of days and duration of cold symptoms Number of fever days Number of vomiting Number of days of antibiotics use Number of days absent from nursery school or kindergarten Number of days and duration of diarrhea | — |
Countries
Japan
Contacts
Public ContactNaoyuki HONMA
Hokkaido Information University Health Information Science Center
Outcome results
None listed