Esophageal pathology and integrated correlates using POEM-based obtained esophageal muscle

Molecular pathological analysis of muscle layers in esophageal motility disorders - Molecular pathological analysis of muscle layers in esophageal motility disorders

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000058347

Enrollment

Registered

2025-07-02

Start date

2025-07-02

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal motility disorders

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients with esophageal motility disorder who have already undergone or are scheduled to undergo esophageal intra-esophageal manometry who are attending or hospitalized at Okayama University Hospital and who will undergo POEM between the date of approval by the head of the research institution and December 31, 2028 2) Patients who can obtain free and voluntary written consent for research participation from the patient 3) Patients between 18 and 90 years of age at the time consent is obtained

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

Measure	Time frame
Abnormal findings (normal contraction, excessive contraction, contraction failure, and relaxation failure) of the esophageal manometry at the site of collection will be compared with the results of the RNA sequencing test and immunostaining results.	—

Countries

Japan

Contacts

Public ContactShoichiro Hirata

Okayama University Hospital Department of Gastroenterology and Hepatology

p6q09uf6@s.okayama-u.ac.jp+81-86-235-7219

Outcome results