Healthy Adult
Conditions
Interventions
Ingestion of test powder containing probiotics for a duration of 8 weeks.
Intake of placebo powder for a duration of 8 weeks.
Sponsors
TES Holdings Co., Ltd.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1)Subjects aged between 35 and 59 years 2)Subjects with skin concerns such as dry skin
Exclusion criteria
Exclusion criteria: 1)Subjects with any chronic disease undergoing medication 2)Subjects with skin diseases, skin needing treatment, or diseases affecting skin 3)Subjects with serious drug/food allergies or a history of them 4)Subjects with malignant tumors, respiratory, liver, renal, cardiac, pulmonary, gastrointestinal, hematologic, endocrine, and metabolic diseases, or history of them 5)Subjects undergoing cosmetic procedures affecting skin, or using strong moisturizing/wrinkle effect cosmetics 6)Subjects habitually consuming food for specified health uses, functional foods, medicines or supplements that affect skin 7)Subjects habitually consuming foods/drinks affecting skin 8)Subjects regularly consuming foods/supplements with lactobacilli, bifidobacteria, oligosaccharides or affecting the intestinal environment 9)Subjects intentionally exposing themselves to sunlight during the test like sunbathing 10)Subjects with a habit of drinking large amounts of alcohol(20g or more/day of pure alcohol) 11)Subjects with a smoking habit 12)Subjects with a BMI under 17kg/m2 or 30kg/m2 or more 13)Subjects defecating under three times a week 14)Subjects with chronic gastrointestinal symptoms like diarrhea 15)Subjects regularly taking medications including laxatives, intestinal regulators, and purgatives 16)Subjects who have taken antibiotics for a week or more in three months prior to the pre-test 17)Subjects with cosmetic procedures/treatments on evaluated areas in two months prior to the pre-test, or during the test 18)Subjects with scars or inflammation on evaluation area, or regular skin irritation there like pre/post menstruation 19)Subjects with irregular lifestyles 20)Subjects planning lifestyle changes during the test 21)Subjects pregnant, planning pregnancy during the test, or breastfeeding 22)Subjects in other drug/food tests in three months prior to the pre-test or scheduled to participate in these tests 23)Subjects judged unsuitable by principal or subinvestigator based on background
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| transepidermal water loss | — |
Secondary
| Measure | Time frame |
|---|---|
| stratum corneum water content, fecal metabolites | — |
Countries
Japan
Contacts
Public ContactRyoma Shimizu
TES Holdings Co., Ltd. Administrative Department of Clinical Trials
Outcome results
None listed