Knee Osteoarthritis
Conditions
Interventions
Tuina group: Standardized Tuina therapy (rubbing, kneading, acupressure on knee - related acupoints like Dubi, Zusanli
2 - 3 times/week, ~30 minutes/session, 1 year) + individualized quadriceps training (2 - 5 times/week) + individualized NSAIDs (ibuprofen/celecoxib, intermittent/continuous as needed)
Non - Tuina grou
Sponsors
Hospital of Chengdu University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Age is 60 years old or older. (2) Knee osteoarthritis (KOA) meets the American College of Rheumatology diagnostic criteria: knee pain in the past 1 month, osteophytes present, and at least one of age is 45 years old or older, morning stiffness is less than 30 minutes, or bone friction sound during knee movement. (3) No prior KOA treatment history. (4) No acute joint infection/inflammation or joint deformity. (5) No severe comorbidities (e.g., heart failure, malignant tumors). (6) No mental illness/cognitive impairment; has sufficient understanding and communication abilities. (7) No tuina therapy contraindications (e.g., skin damage, fractures, severe osteoporosis, coagulation disorders). (8) Participant and family members understand the study and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Age is younger than 60 years old. (2) KOA does not meet the American College of Rheumatology diagnostic criteria. (3) Has received prior KOA treatment. (4) With acute joint infection/inflammation or joint deformity. (5) With severe comorbidities (e.g., heart failure, malignant tumors). (6) With mental illness/cognitive impairment; lacks sufficient understanding and communication abilities. (7) With tuina therapy contraindications (e.g., skin damage, fractures, severe osteoporosis, coagulation disorders). (8) Participant or family members do not understand the study or refuse to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is the change in frailty status measured by the Fried Frailty Phenotype Score (FFPS) at the end of the 12-month intervention period. | — |
Secondary
| Measure | Time frame |
|---|---|
| Key secondary outcomes include the changes in Frailty Index (FI), gait speed, 6-minute walk distance (6MWD) and health-related quality of life evaluated by SF-36 at the end of the one-year intervention. | — |
Countries
Asia(except Japan)
Contacts
Public ContactXi Yang
Hospital of Chengdu University of Traditional Chinese Medicine Massage Department
Outcome results
None listed