Cardiac diseases requiring cardiovascular surgery with cardiopulmonary bypass (regurgitant valvular disease, stenotic valvular disease, aortic aneurysm, ischemic heart disease)
Conditions
Interventions
None listed
Sponsors
Nagasaki University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Age: 18 years or older Surgical procedure: Cardiovascular surgery using cardiopulmonary bypass (including valve replacement, valve repair, aortic replacement, and coronary artery bypass grafting) Diseases: Cardiac diseases for which the above surgical procedures are indicated (such as regurgitant valvular disease, stenotic valvular disease, aortic aneurysm, and ischemic heart disease) Timing of surgery to be included: From the date of approval by the institution's director to March 31, 2026 Consent: Patients who have provided written informed consent themselves or through a legally authorized representative
Exclusion criteria
Exclusion criteria: Patients with antiphospholipid syndrome Patients currently participating in a clinical trial or specified clinical research
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ACT values and the differences between measurement cartridges (JACT-LR and JACT+) at the following time points: induction of anesthesia, after protamine reversal following weaning from cardiopulmonary bypass, and at the end of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation between ACT values obtained from each measurement device and APTT | — |
Countries
Japan
Contacts
Public ContactTakayuki Morimoto
Nagasaki University Hospital Department of Anesthesiology
Outcome results
None listed