Palatine tonsillar hypertrophy, Adenoid hypertrophy, Chronic tonsillitis (including IgA nephropathy)
Conditions
Interventions
None listed
Sponsors
Kyushu University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with palatine tonsillar hypertrophy, chronic tonsillitis (including IgA nephropathy), or adenoid hypertrophy at the Department of Otorhinolaryngology - Head and Neck Surgery, Kyushu University Hospital or collaborating institutions, and who have undergone palatine tonsillectomy or adenoidectomy between the date of research approval and March 31, 2030. 2.Patients (or their legal representatives) who fully understand the research plan and are capable of providing informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients with malignant tumors or those undergoing surgery due to suspected malignancy. 2.Patients whom the investigator deems unsuitable for inclusion in the study for any other reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Phenotypic analysis of tissue-resident immune cells and evaluation of their proliferation and aggregate formation in vitro | — |
Secondary
| Measure | Time frame |
|---|---|
| Establishment of an organoid-based platform for recapitulating immune activation and differentiation | — |
Countries
Japan
Contacts
Public ContactDaisuke Murakami
Kyushu University Hospital Otorhinolaryngology - Head and Neck Surgery
Outcome results
None listed