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Retinal blood flow testing for physiological load in healthy adults

Retinal blood flow testing for physiological load in healthy adults - Retinal blood flow testing for physiological load

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000058188
Enrollment
16
Registered
2025-06-16
Start date
2025-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic retinopathy

Interventions

(1) Measurement of mean blood pressure by arm insertion sphygmomanometer (2) Measurement of intraocular pressure by non-contact tonometer (3) Mydriasis by a single tropicamide eye drop (4) Oxybu

Sponsors

Asahikawa Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Persons 18 years of age or older without diabetic disease

Exclusion criteria

Exclusion criteria: 1) Patients with a history of diabetes, hypertension, or dyslipidemia 2) Patients who are taking medication 3) Those with a history of smoking 4) Those with a history of eye disease and in the process of treatment.

Design outcomes

Primary

MeasureTime frame
Laser speckle flowography (LSFG) will be used to evaluate resting retinal blood flow, retinal blood flow every 4 seconds during 1 minute of 8 Hz flicker stimulation, and retinal blood flow every 4 seconds during 1 minute after the end of flicker stimulation. Similarly, LSFG will be used to evaluate resting retinal blood flow, retinal blood flow every minute during 5 minutes of exercise with 2-3 kg dumbbells, and retinal blood flow after the end of exercise. Ocular perfusion pressure and retinal blood flow changes during each loading test from rest will be compared.

Countries

Japan

Contacts

Public ContactTaiji Nagaoka

Asahikawa Medical University Department of Ophthalmology

ganka@asahikawa-med.ac.jp0166682543

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026