A Retrospective Observational Study Investigating the Relationship Between Thymic Carcinoma Histopathology and Postoperative Outcomes

A Retrospective Observational Study Investigating the Relationship Between Thymic Carcinoma Histopathology and Postoperative Outcomes - A Retrospective Observational Study Investigating the Relationship Between Thymic Carcinoma Histopathology and Postoperative Outcomes

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000058125

Enrollment

100

Registered

2025-06-10

Start date

2022-11-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thymic carcinoma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who underwent surgery for thymic carcinoma at Okayama University Hospital or collaborating institutions between January 2010 and December 2021. 2. Patients aged 20 years or older at the time of surgery. 3. Sex: male or female. 4. Inpatient or outpatient status.

Exclusion criteria

Exclusion criteria: 1. Patients with insufficient remaining clinical or pathological data for analysis.

Design outcomes

Primary

Measure	Time frame
Association between tumor-infiltrating lymphocytes (TILs), tertiary lymphoid structures (TLSs), and peripheral blood-derived biomarkers (NLR, PLR, LMR, PNI, and mGPS) using surgical tissue specimens, and postoperative survival in patients with thymic carcinoma.	—

Secondary

Measure	Time frame
Evaluation of postoperative recurrence, cause-specific mortality, recurrence-free survival (RFS), and progression-free survival (PFS). Analysis of overall survival and recurrence-free survival stratified by surgical procedure.	—

Countries

Japan

Contacts

Public ContactTatsuya Hayashi

Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University Department of General Thoracic Surgery and Breast and Endocrinological Surgery

p27j13yv@s.okayama-u.ac.jp0862357265

Outcome results