Establishment of a New Classification of Calcific Aortic Stenosis: Multicenter Aortic Stenosis Research Observational Network

Establishment of a New Classification of Calcific Aortic Stenosis: Multicenter Aortic Stenosis Research Observational Network - MARON study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000058120

Enrollment

1000

Registered

2025-09-01

Start date

2025-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Stenosis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: From April 2016 to March 2025, echocardiographic follow-up will be performed for patients with moderate or severe AS, with at least 6 months between the dates of the echocardiographic follow-up. Calcified tricuspid aortic valve stenosis

Exclusion criteria

Exclusion criteria: Bicuspid valve AS Congenital AS After AVR/TAVR dialysis

Design outcomes

Primary

Measure	Time frame
Change in AV peak velocity at 12 months	—

Secondary

Measure	Time frame
Changes in echocardiographic parameters at 6 and 12 months Change in aortic valve calcification score/calcification density at 12 months TAVR/SAVR Incidence of heart failure, cardiovascular death, and all-cause mortality	—

Countries

Japan

Contacts

Public ContactHironobu Toda

Okayama University Hospital Department of Cardiovascular medicine

hiromail1979@s.okayama-u.ac.jp0862357351

Outcome results