The target diseases will include a broad spectrum of cardiovascular diseases, primarily focusing on coronary artery disease. This includes stable angina, unstable angina, myocardial infarction, and heart failure.
Conditions
Interventions
None listed
Sponsors
Shingo Kato, Department of Diagnostic Radiology, Yokohama City University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Original studies reporting hazard ratios (HRs) for major adverse cardiovascular events (MACE), cardiac mortality, or all-cause mortality in relation to pericoronary fat attenuation index (FAI) measured by coronary computed tomography angiography (CCTA) Clear documentation of the coronary artery segment analyzed (right coronary artery [RCA], left anterior descending artery [LAD], or left circumflex artery [LCX]) Human studies Articles published in English
Exclusion criteria
Exclusion criteria: Exclusion Criteria: Studies not reporting prognostic outcomes (MACE, cardiac mortality, or all-cause mortality) Review articles, case reports, and non-human studies Non-English language articles
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The pericoronary fat attenuation index (FAI), derived from coronary computed tomography angiography (CCTA), is a noninvasive imaging biomarker that reflects inflammation-induced changes in perivascular adipose tissue (PVAT); this study aims to evaluate the prognostic value of FAI for major adverse cardiovascular events (MACE), cardiac mortality, and all-cause mortality, with subgroup analyses based on coronary artery (right coronary artery [RCA], left anterior descending artery [LAD], and left circumflex artery [LCX]) and geographic region (Asian vs. non-Asian populations). | — |
Countries
Japan
Contacts
Public ContactShingo Kato
Yokohama City University Hospital Department of Diagnostic Radiology
Outcome results
None listed