Effects of sex, menstrual cycle, and exercise training on cutaneous vasodilation in females and the mechanisms

Effects of sex, menstrual cycle, and exercise training on cutaneous vasodilation in females and the mechanisms - Effects of sex, menstrual cycle, and exercise training on cutaneous vasodilation in females and the mechanisms

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000058091

Enrollment

Registered

2025-06-12

Start date

2025-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Application of a nitric oxide synthase inhibitor (2% L-NAME) using transdermal iontophoresis or intradermal microdialysis Application of saline using transdermal iontophoresis or intradermal microdial

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy males and females between the ages of 18 and 40

Exclusion criteria

Exclusion criteria: 1) Smoker, obese individuals 2) Individuals experienced any cardiovascular disease 3) Individuals with cardiac arrhythmia 4) Individuals with asthma 5) Individuals with gastrointestinal disease 6) Individuals with epilepsy 7) Individuals taking any medications drugs 8) Individuals experienced fainting during blood sampling 9) Individuals who have been considered to exclude the participants based on a researcher

Design outcomes

Primary

Measure	Time frame
Cutaneous vascular conductance	—

Countries

Japan

Contacts

Public ContactYumi Okamoto

Niigata University of Health and Welfare Faculty of Health Sciences

yumi-okamoto@nuhw.ac.jp025-257-4590

Outcome results