Evaluation of the Effectiveness of Transcatheter Valve Therapies from the Perspective of Well-being in Elderly Patients Requiring Long-Term Care or Support

Evaluation of the Effectiveness of Transcatheter Valve Therapies from the Perspective of Well-being in Elderly Patients Requiring Long-Term Care or Support - DESIRE Registry (Dependent Elderly Structural heart disease InteREvention Registry)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000058072

Enrollment

250

Registered

2025-06-09

Start date

2026-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Stenosis, Mitral Regurgitation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing TAVI or TEER at St Marianna University Hospital who are certified or currently applying for certification as needing long-term care or support under long-term care insurance system in Japan.

Exclusion criteria

Exclusion criteria: Patients who do not provide informed consent. Patients under the age of 20.

Design outcomes

Primary

Measure	Time frame
Unfavorable outcome defined as all-cause mortality or a Kansas City Cardiomyopathy Questionnare (KCCQ) score below 45 or a decline of 10 points or more in KCCQ at one year after the procedure (Valve Academic Research Consortium-3)	—

Secondary

Measure	Time frame
1. To assess changes in quality of life (QOL), activities of daily living (ADL), patient satisfaction, and social functioning at baseline, discharge, 1 month, 12 months, 36 months, and 60 months post-procedure. 2. To identify clinical and procedural factors associated with improved or worsened outcomes from the perspective of well-being.	—

Countries

Japan

Contacts

Public ContactYuki Harashima

St. Marianna University School of Medicine Nursing Department

yuki.harashima@marianna-u.ac.jp044-977-8111

Outcome results