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Pathophysiological evaluation of bipolar disorder and depression using autonomic, EEG and cerebral blood flow measurements

Pathophysiological evaluation of bipolar disorder and depression using autonomic, EEG and cerebral blood flow measurements - Pathophysiological evaluation of bipolar disorder and depression using physiological indices

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000058055
Enrollment
60
Registered
2025-06-02
Start date
2013-03-25
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bipolar disorder, depression, anxiety disorder, adjustment disorder, neurodevelopmental disorder

Interventions

The sensors include a wearable ECG sensor placed on the chest (RF-ECG2, GM3 Co.), a wrist-band-type autonomic measurement device around the wrist (Embrace-Plus, Empatica Co.), a wearable EEG and auton

Sponsors

Shizuoka Saiseikai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The patients who visit the department of psychiatry at Shizuoka Saiseikai General Hospital are recruited to this study after giving us their consent to participate in it.The protocol of this study has been approved by the Institutional Review Board of Shizuoka Saiseikai General Hospital.

Exclusion criteria

Exclusion criteria: Those who have somatic disorders that do not allow the stable measurement are excluded. The patients who show adverse effects due to the measurement are also excluded.

Design outcomes

Primary

MeasureTime frame
Heart rate, heart rate variability, skin conductance, skin temperature are used as autonomic indices. Power spectrum analysis of EEG data was conducted to evaluate brain electrical activity. Brain blood flow was calculated at the forehead. The pathophysiological profiles of the disorders at rest as well as during mental tasks are evaluated using these indices.

Countries

Japan

Contacts

Public ContactToshikazu Shinba

Shizuoka Saiseikai General Hospital Department of Psychiatry

t156591@siz.saiseikai.or.jp+81542856171

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026