Prostate cancer patients receiving hormonal therapy (androgen deprivation therapy)
Conditions
Interventions
All participants are asked to perform physical exercise in their daily lives. Physical excercise is performed as a home program. A home program includes excercises recommended by the Ministry of Heal
1.Walking of 8000 steps a day, three times per week, 2.Diary locomotor-training. All subjects were asked to keep a diary about how well they were able to perform these exercises. Based on a diary and
patients who performed a lot of exercise therapy (80% or more), ones who performed it to a certain extent (40-80%), and the group who performed it very little (less than 40%). All data are compared in
Sponsors
Kanazawa University Graduate School of Medical Science
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. The patients with locally advanced prostate cancer receiving hormonal therapy and radical radiotherapy, or the patients with painless metastatic prostate cancer receiving hormonal therapy. 2. The patients with a written informed consent to attend the present study. 3. The patients aged over 20 years.
Exclusion criteria
Exclusion criteria: 1. The prostate cancer therapy patients with metastatic prostate cancer and with a risk of bone fracture (bone scan index of more than 3.0% based on bone scan). 2. The patients with cardiovascular diseases, locomotor diseases, or neurologic disorders, which are not suitable for exercise therapy. 3. The patients who are deemed inappropriate by an attending doctor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in systemic muscle mass, Lower limb muscle mass, and grip power (items associated with sarcopenia) 3, 6, 9. 12, 18, 24, 30, and 36 months after initiation of ADT. | — |
Secondary
| Measure | Time frame |
|---|---|
| The following items before and after the start of treatment: 1. Height, weight, BMI, body fat percentage, and waist circumference 2. Locomotor syndrome test 3. Short Physical Performance Battery 4. Clinical Frailty Scale 5. Bone mineral content (evaluated at the femoral neck) 6. Skeletal muscle index at L3 level on CT (L3-SMI) | — |
Countries
Japan
Contacts
Public ContactKazuyoshi Shigehara
Kanazawa University Graduate School of Medical Science Department of Integrative Cancer Therapy and Urology
Outcome results
None listed