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A study of the effects of Cyclo Isomaltooligosaccharide intake on plaque inhibition and caries development and progression

A study of the effects of Cyclo Isomaltooligosaccharide intake on plaque inhibition and caries development and progression - A study of the effect of Cyclo Isomaltooligosaccharide intake on dental caries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000057937
Enrollment
100
Registered
2025-05-30
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental caries

Interventions

Intake of test food containing 600mg Cyclo Isomaltooligosaccharide per one day Intake of test food not containing 600mg Cyclo Isomaltooligosaccharide per one day

Sponsors

Meikai University
Lead Sponsor
Chuo University
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: -Those who are not undergoing active dental treatment. -Those who have no caries requiring treatment as determined by a prior dental checkup. -Those who have received an explanation of the study contents and have given written consent to participate in the study.

Exclusion criteria

Exclusion criteria: Those with serious systemic illnesses such as internal medicine

Design outcomes

Primary

MeasureTime frame
About 9 months after starting intake - Visual examination of caries epidemiological indicators (ICDAS and DMF) - Quantification of salivary biomarkers (S-IgA/LL-37/defensin) - Analysis of oral flora During intake period Interviews regarding condition, vitality, health, etc., such as toothache, hypersensitivity,feeling unwell or having a cold

Secondary

MeasureTime frame
About 9 months after starting intake - Quantification of salivary biomarkers (S-IgA/LL-37/defensin) - Analysis of oral flora

Countries

Japan

Contacts

Public ContactGEN TANABE

Meikai University Department of Sports Dentistry

gen.spmd@dent.meikai.ac.jp049-279-2745

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026