A prospective observational study of corneal stromal transplantation for advanced keratoconus

A prospective observational study of corneal stromal transplantation corneal for advanced keratoconus - A study of corneal stromal transplantation corneal for advanced keratoconus

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000057925

Enrollment

Registered

2025-06-01

Start date

2024-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

keratoconus, keratoectasia

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients aged 14 years or older of advanced keratoconus or keratoectasia are classified as stage 3 or 4 of Amsler-Krumeich classification

Exclusion criteria

Exclusion criteria: Age is under 14 years old.

Design outcomes

Primary

Measure	Time frame
best spectacle-corrected visual acuity (BSCVA), and refraction (K-value) at 1 month, 3 months, 6 months, and 1 year postoperatively. Intraoperative and postoperative complications.	—

Secondary

Measure	Time frame
best spectacle-corrected visual acuity (BSCVA), best contact lens-corrected visual acuity (BCLVA), AS-OCT-based corneal tomography measurements, endothelial cell density, refraction (K-value), and intraoperative, postoperative complications anterior and posterior HOAs, contact lens intolerance, and evaluation of the corneal structure using confocal microscopy at 1 month, 3 months, 6 months, and 1 year postoperatively.	—

Measure

Time frame

best spectacle-corrected visual acuity (BSCVA), best contact lens-corrected visual acuity (BCLVA), AS-OCT-based corneal tomography measurements, endothelial cell density, refraction (K-value), and intraoperative, postoperative complications anterior and posterior HOAs, contact lens intolerance, and evaluation of the corneal structure using confocal microscopy at 1 month, 3 months, 6 months, and 1 year postoperatively.

—

Countries

Japan

Contacts

Public ContactTakahiko Hayashi

Nihon University Hospital Opthalmology

htakahiko-aikou@umin.ac.jp03-3972-8111

Outcome results