Healthy female volunteers
Conditions
Interventions
Smell the test products-including aromas
Smell the control product
Sponsors
KOBAYASHI Pharmaceutical Co.,Ltd.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: (1) Women aged 20 to 50 at the time of obtaining informed consent (2) Those with a BMI of 18.5 or more and less than 25.0 kg/m2 (3) Individuals who have received a sufficient explanation of the study, can understand the contents, and can give their own informed consent
Exclusion criteria
Exclusion criteria: (1) People who dislike citrus scents such as lemon, herbal scents such as lavender and eucalyptus, and woody scents such as incense and cypress. (2) People who have a habit of smoking (excluding those who have quit smoking for more than six months) (3) Those taking foods for specified health uses, foods with functional claims (GABA, lactobacillus drinks for stress relief, etc.), health foods (including supplements), etc. that may affect the study (4) Persons whose eyes (exotropia, esotropia, ptosis, etc.) or eyelashes are not suitable for pupil measurement (5) Persons who have dry eyes or other conditions that impede pupil measurement (6) Persons who are aware of claustrophobia or nyctophobia (7) Persons who are aware of daily daytime sleepiness or who have irregular sleep hours due to night shifts, etc. (8) People who are taking medications on an ongoing basis (9) People who are aware of poor circulation (including people who feel cold hands and feet even in summer) (10) People who have stuffy noses due to allergic rhinitis, or who cannot distinguish between scents (11) Persons with external wound at the measurement site (12) Persons currently participating in clinical trials of other drugs or health foods, or who have completed the trial within 4 weeks (13) Persons with symptoms of skin diseases such as atopic dermatitis (14) Persons with a history or current history of serious diseases of the heart, liver, kidneys, digestive system, etc. (15) Persons who are pregnant, wish to become pregnant, or are breastfeeding (16) Individuals with chemical sensitivity or allergies to essential oils, alcohol, or synthetic fragrances (17) Individuals who have experienced or may experience nausea from the smell of alcohol or synthetic fragrances (18) Individuals who are deemed inappropriate for participation in this study by the principal investigator, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pupillary light reflex | — |
Secondary
| Measure | Time frame |
|---|---|
| Subjective questionnaire/skin temperature/brain activity | — |
Countries
Japan
Contacts
Public ContactYuri Tanaka
KOBAYASHI Pharmaceutical Co.,Ltd. Personal & House Care Product Development Dpmt R&D Headquarters
Outcome results
None listed