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Meta-analysis of Diagnostic Accuracy of Deep Learning Based on Ultra-Widefield Fundus Imaging for Retinal Detachment

Systematic Review and Meta-analysis of Diagnostic Accuracy of Deep Learning Using Ultra-Widefield Fundus Imaging for Retinal Detachment - Systematic Review of DL*UWF for RD Diagnosis

Status
Active, not recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000057903
Enrollment
Unknown
Registered
2025-05-30
Start date
2025-05-24
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Retinal Detachment

Interventions

None listed

Sponsors

Yokohama City University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: This meta-analysis includes studies that evaluate the diagnostic accuracy - specifically sensitivity and specificity - of deep learning algorithms using ultra-widefield fundus images for the detection of retinal detachment. Eligible study designs include case-control, cross-sectional, prospective, and retrospective observational studies. Studies must report sufficient data to allow calculation of diagnostic accuracy metrics (true positives, false positives, false negatives, true negatives). While peer-reviewed original articles are primarily targeted, conference abstracts may also be included if they contain adequate diagnostic information.

Exclusion criteria

Exclusion criteria: Studies that report only sensitivity or specificity, or that lack sufficient data to calculate diagnostic accuracy metrics, will be excluded. In addition, studies suspected of using duplicate datasets and non-original articles such as case reports, reviews, and editorials will also be excluded.

Design outcomes

Primary

MeasureTime frame
Sensitivity and specificity of deep learning algorithms using ultra-widefield fundus images for the diagnosis of retinal detachment, based on the assessment at the time of diagnosis in each included study

Secondary

MeasureTime frame
Key secondary outcomes include the area under the summary receiver operating characteristic curve (AUC) at the time of diagnosis, the diagnostic odds ratio (DOR), between-study heterogeneity assessed by the I^2 statistic, and risk of bias evaluated using the QUADAS-2 tool.

Countries

Japan

Contacts

Public ContactYuki Mizuki

Yokohama City University Hospital Department of Ophthalmology

mizuki.yuk.xj@yokohama-cu.ac.jp0457872683

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026