Effect of oral application of povidone-iodine on the number of bacteria entering the lower respiratory tract of intubated patients

Effect of oral application of povidone-iodine on the number of bacteria entering the lower respiratory tract of intubated patients - Effect of oral application of povidone-iodine on the number of bacteria entering the lower respiratory tract of intubated patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000057899

Enrollment

Registered

2025-05-19

Start date

2023-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intubated patients with cuffed tracheostomy tubes

Interventions

Isodine application group Brushing group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) A cuffed tracheal cannula is in place 2) Age at least 18 years old at the time consent is obtained 3) Gender: any gender 4) Name of disease: No questions asked 5) Patients who have received a thorough explanation of their participation in this study,and who have obtained the free and voluntary consent of the research subject or the research subject's surrogate, based on a thorough understanding of the subject's condition.

Exclusion criteria

Exclusion criteria: 1) edentulous jaw 2) History of iodine allergy 3) Patients who have refused to participate in this study 4) Other patients deemed inappropriate as research subjects by the principal investigator

Design outcomes

Primary

Measure	Time frame
Total bacteria in cuff upper reservoir by Real-time PCR	—

Countries

Japan

Contacts

Public ContactYuki Sakamoto

Kansai medical university medical center Oral surgery

s.yukioutdoor@gmail.com09086076285

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026